Pre-clinical fatty acid composition estimate of adipose tissue using echo planar spectroscopic imaging (EPSI) at 4.7T

International audience; This pilot study performed on a preclinical system at 4.7T shows the feasibility of using the echo planar spectroscopic imaging sequence (EPSI with a spin echo) to quantify the fatty acid composition. This sequence permitted to image separately each resonating component of fat spectrum. The signal of the EPSI sequence was compared with more standard spectroscopic sequence used for the fatty acid quantification (PRESS). Thequantification results from the EPSI sequence on calibrated phantom were consistent with gas chromatography theoretical values. The in vivoacquisition showed a significant difference of the fatty acid composition between the subcutaneous and the visceral adipose tissue, consistent withpublished monovoxel results.Abstract available: https://index.mirasmart.com/ISMRM2019/PDFfiles/1937.html