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Involvement of the serotonin pathway in ileal neruomotor dysfunction associated with TLR2 and TLR4 inhibition in juvenille mice

Authors :
Marsilio, I.
Caputi, V.
Cerantola, S.
Latorre Duque, E.
Paquola, A.
Pattarello, A.
Orso, G.
Mesonero, J.E.
Bertazzo, A.
Giron, M.C.
Source :
Zaguán. Repositorio Digital de la Universidad de Zaragoza, instname
Publication Year :
2017

Abstract

Objective: Oxidized phospholipids (OxPAPC) inhibit TLR2-and TLR4-dependent signalling recognized to be involved in ensuring enteric nervous system (ENS) integrity. This study aimed to evaluate the effects of in vivo OxPAPC administration on ileal contractility and serotonin pathway in juvenile mice.

Details

Language :
English
Database :
OpenAIRE
Journal :
Zaguán. Repositorio Digital de la Universidad de Zaragoza, instname
Accession number :
edsair.dedup.wf.001..759aa989f982b26242bdd93a8d5a3310