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Impact de l’âge sur la mortalité des patients traumatisés médullaires hospitalisés en réanimation [Impact of age on mortality in patients with acute traumatic spinal cord injury requiring intensive care]

Authors :
Seguin, Philippe
Godard, A.
Le Maguet, Pascale
Launey, Yoann
Laviolle, Bruno
Mallédant, Yannick
Foie, métabolismes et cancer
Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )
Service d'anesthésie réanimation chirurgicale [Rennes]
Université de Rennes (UR)-Hôpital Pontchaillou
Service de pharmacologie biologique et toxicologie [Rennes]
Hôpital Pontchaillou-CHU Pontchaillou [Rennes]
Université de Rennes 1 (UR1)
Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )
Hôpital Pontchaillou-Université de Rennes 1 (UR1)
Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)
Le Corre, Morgane
Source :
Annales Françaises d'Anesthésie et de Réanimation, Annales Françaises d'Anesthésie et de Réanimation, 2012, 31 (3), pp.196-202. ⟨10.1016/j.annfar.2011.10.019⟩, Annales Françaises d'Anesthésie et de Réanimation, Elsevier Masson, 2012, 31 (3), pp.196-202. ⟨10.1016/j.annfar.2011.10.019⟩
Publication Year :
2012
Publisher :
HAL CCSD, 2012.

Abstract

National audience; Objective To evaluate the impact of age (< or ≥ 65 ans) on hospital mortality in traumatic spinal cord injury requiring intensive care. Design Retrospective, monocenter. Patients and methods A total of 131 patients greater or equal to 15 years (< 65 years, n = 109 and ≥ 65 years, n = 22) was analyzed (cervical, n = 71; thoracolumbar, n = 60), over a 10 years period (1998-2008). The hospital and long-term mortality were studied. The risks factors of death were searched by a uni- and multivariate analysis. Intensive care unit (ICU) discharge and long-term neurological recovery, and long-term functional independence measure (FIM) were assessed. Results Hospital mortality was increased in patients greater or equal to 65 years (41% vs 6%, P < 0.001) and long term mortality was not different between the two groups (31% vs 12%, P = 0.150). The risks factors of death were age (HR = 3.44; IC 95%: 1.53-7.72, P = 0.028), previous coronary disease (HR = 3.64; IC 95%: 1.25-10.65; P = 0.018) and fall injury (HR = 2.40; IC 95%: 1.15-5.00, P = 0.020). Among survivors, incompletes forms (Frankel B, C, D, E) were significantly more frequent in older patients at ICU discharge and long term follow up. At long term, FIM was similar in the two groups except a better sphincter control in patient greater or equal to 65 years. Conclusion Mortality rate of older people (≥ 65 years) were greater than those in younger people, mainly caused by an increased hospital mortality. Among survivors, the neurological recovery was better in patients' greater or equal to 65 years, and was associated with a functional status at least comparable than in the youngest patients.

Details

Language :
French
ISSN :
07507658
Database :
OpenAIRE
Journal :
Annales Françaises d'Anesthésie et de Réanimation, Annales Françaises d'Anesthésie et de Réanimation, 2012, 31 (3), pp.196-202. ⟨10.1016/j.annfar.2011.10.019⟩, Annales Françaises d'Anesthésie et de Réanimation, Elsevier Masson, 2012, 31 (3), pp.196-202. ⟨10.1016/j.annfar.2011.10.019⟩
Accession number :
edsair.dedup.wf.001..721db22a825f6488471f7f7eb4b4d95b