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Investigating candidate genes for Pentachlorophenol detoxification in Drosophila melanogaster

Authors :
Monti M.M.
Pedata P.A.
Van Der Lee T.A.J.
Testa A.
Di Matteo A.
Rao M.A.
Monti, M. M.
Pedata, P. A.
Van Der Lee, T. A. J.
Di Matteo, A.
Rao, M. A.
Testa, A.
Source :
1st Global Virtual Conference, pp. 447–450, 8th-12th April 2013, info:cnr-pdr/source/autori:Monti M.M., Pedata P.A.,Van Der Lee T.A.J., Testa A., Di Matteo A., Rao M.A./congresso_nome:1st Global Virtual Conference/congresso_luogo:/congresso_data:8th-12th April 2013/anno:2013/pagina_da:447/pagina_a:450/intervallo_pagine:447–450
Publication Year :
2012

Abstract

A 90K Custom microarray was employed to highlight the effects of Pentachlorophenol on Drosophila melanogaster transcriptome in order to identify potential metabolic pathways involved in detoxification of polyhalogenated aromatic hydrocarbons. Microarray assays were performed on mRNA from early third instar larvae challenged with different PCP concentrations (0, 20 and 2000 ppm) incorporated in dietary supply. Bayesian Estimation of Temporal Regulation (BETR) analysis identified a set of 514 Differentially Expressed (DE) mRNAs among the control and the treated larvae (p

Details

Language :
English
Database :
OpenAIRE
Journal :
1st Global Virtual Conference, pp. 447–450, 8th-12th April 2013, info:cnr-pdr/source/autori:Monti M.M., Pedata P.A.,Van Der Lee T.A.J., Testa A., Di Matteo A., Rao M.A./congresso_nome:1st Global Virtual Conference/congresso_luogo:/congresso_data:8th-12th April 2013/anno:2013/pagina_da:447/pagina_a:450/intervallo_pagine:447–450
Accession number :
edsair.dedup.wf.001..57a651521ec8613307e90df2c1c730ef