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Responses of pigs divergently selected for cortisol response or feed efficiency to an ACTH challenge

Authors :
Gilbert, Hélène
Mormede, Elena
Louveau, Isabelle
Ruesche, Julien
Gress, Laure
Billon, Yvon
Mormède, Pierre
Larzul, Catherine
Génétique Physiologie et Systèmes d'Elevage (GenPhySE )
Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT)
Institut National Polytechnique (Toulouse) (Toulouse INP)
Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National Polytechnique (Toulouse) (Toulouse INP)
Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-École nationale supérieure agronomique de Toulouse [ENSAT]
Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] (PEGASE)
AGROCAMPUS OUEST-Institut National de la Recherche Agronomique (INRA)
UE 1372 Génétique, Expérimentation et Système Innovants
Institut National de la Recherche Agronomique (INRA)-Génétique animale (G.A.)-Physiologie Animale et Systèmes d'Elevage (PHASE)
Institut National de la Recherche Agronomique (INRA)-Génétique, Expérimentation et Système Innovants (GenESI)
École nationale supérieure agronomique de Toulouse [ENSAT]-Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire de Toulouse (ENVT)
Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées
Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST
Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)
Génétique, Expérimentation et Système Innovants (GenESI)
Institut National de la Recherche Agronomique (INRA)
Source :
68. Annual Meeting of the European Association for Animal Production (EAAP), 68. Annual Meeting of the European Association for Animal Production (EAAP), Aug 2017, Tallinn, Estonia. Wageningen Academic Publishers, 2017, Annual Meeting of the European Association for Animal Production, Book of Abstract of the 68th Annual Meeting of the European Federation of Animal. 1ère Ed. (23), 2017; 68. Annual Meeting of the European Association for Animal Production (EAAP), Tallinn, EST, 2017-08-28-2017-09-01, 240-240, 68. Annual Meeting of the European Association for Animal Production (EAAP), Aug 2017, Tallinn, Estonia. Wageningen Academic Publishers, Annual Meeting of the European Association for Animal Production, 23 (1ère Ed.), 2017, Annual Meeting of the European Association for Animal Production
Publication Year :
2017
Publisher :
HAL CCSD, 2017.

Abstract

Selection for feed efficiency can impair the animal’s ability to respond to stress. A key driver of this response is the hypothalamo-pituitary-adrenal (HPA) axis, which releases cortisol in response to stressors. Injection of a normalized dose of adrenocorticotropic hormone (ACTH) to stimulate cortisol release by the adrenal cortex is a standardized method to evaluate the activity of the HPA axis independently of the animal’s perception of stress. It has been used to select during three generations a highCortisol line and a lowCortisol line, that had divergent cortisol levels 1 h after ACTH injection (H1, peak of the response). A trial was set up to compare the responses to ACTH of these two lines and those of two other lines divergently selected for residual feed intake (RFI, measure of net feed efficiency) during nine generations. At 6 weeks of age, 48 pigs per line were tested. Blood samples were collected before and 1 (H1) and 4 h after injection (H4) when cortisol is expected to return to basal level. In the Cortisol lines, plasma cortisol was multiplied by 2 (P

Details

Language :
English
Database :
OpenAIRE
Journal :
68. Annual Meeting of the European Association for Animal Production (EAAP), 68. Annual Meeting of the European Association for Animal Production (EAAP), Aug 2017, Tallinn, Estonia. Wageningen Academic Publishers, 2017, Annual Meeting of the European Association for Animal Production, Book of Abstract of the 68th Annual Meeting of the European Federation of Animal. 1ère Ed. (23), 2017; 68. Annual Meeting of the European Association for Animal Production (EAAP), Tallinn, EST, 2017-08-28-2017-09-01, 240-240, 68. Annual Meeting of the European Association for Animal Production (EAAP), Aug 2017, Tallinn, Estonia. Wageningen Academic Publishers, Annual Meeting of the European Association for Animal Production, 23 (1ère Ed.), 2017, Annual Meeting of the European Association for Animal Production
Accession number :
edsair.dedup.wf.001..47fbc9ac8cfa908efd9176be48d84381