The therapeutic effect of pour-on administered cypermethrin in Psoroptes cunuculi infestation in rabbits

Cenesiz, Metin/0000-0003-2494-1959; Beyhan, Yunus Emre/0000-0002-1696-4803 WOS: 000345816500003 In this study, clinical and in vivo acaricidal effects of pour-on administered cypermethrin in rabbits with Psoroptes cuniculi were evaluated. Totally 24 rabbits were used in the study. Sixteen rabbits, naturally infested with P. cuniculi were randomly divided into two equal experimental groups and cypermethrin was pour-on administered 5 mg/kg (Group I) and 10 mg/kg (Group II) as a single dose. Also, 8 healthy animals (non-infested with P. cuniculi) exposed only saline were used for the control group. Psoroptic mange was diagnosed and monitored in the experimental groups by otoscopic and microscopic evaluations on Day 0 (pretreatment) and Days 1, 3, 7, 14, and 21 after the treatment. Clinical findings about psoroptic mange were scored, blood cypermethrin concentrations and haematological parameters were determined on the evaluation days. Six rabbits from Group I had P. cuniculi and a statistically important difference was determined between number of infested rabbits of Group I and Group II on Day 21 (p