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Exhaled nitric oxide in premature and mature infants during the first months of life:Exhaled Nitric Oxide in neonates – a review

Authors :
Goth, Fanny E.M.
Schmidt, Birgitte J.
Agertoft, Lone
Jørgensen, Inger Merete
Source :
Goth, F E M, Schmidt, B J, Agertoft, L & Jørgensen, I M 2021, ' Exhaled nitric oxide in premature and mature infants during the first months of life : Exhaled Nitric Oxide in neonates – a review ', Nitric Oxide-Biology and Chemistry, vol. 113-114, pp. 7-12 . https://doi.org/10.1016/j.niox.2021.04.005, Goth, F E M, Schmidt, B J, Agertoft, L & Jørgensen, I M 2021, ' Exhaled nitric oxide in premature and mature infants during the first months of life : Exhaled Nitric Oxide in neonates – a review ', Nitric oxide, vol. 113-114, pp. 7-12 . https://doi.org/10.1016/j.niox.2021.04.005
Publication Year :
2021

Abstract

AIM: In this review, we aim to describe how exhaled Nitric Oxide(NO) changes during the first months of life in premature and mature infants.METHOD: Review of the literature up to August 2020, on online, tidal breathing NO measurements in unsedated infants. The association between Fractional exhaled NO(FeNO) values, postnatal age, and prematurity was analysed using linear mixed modeling and Spearman's rank correlation.RESULTS: Median FeNO during the first months of life was 5.9 and 8.5 ppb in premature and mature infants, respectively. The linear mixed model analysis showed a significant effect of postnatal age on FeNO (p = 0.007).CONCLUSION: Our study suggests that FeNO is higher in mature infants than premature infants, and FeNO increased with postnatal age at approximately the same pace in both groups.

Subjects

Subjects :
Exhaled nitric oxide
Neonatal
Lung development
respiratory system
Premature
respiratory tract diseases

Details

Language :
English
Database :
OpenAIRE
Journal :
Goth, F E M, Schmidt, B J, Agertoft, L & Jørgensen, I M 2021, ' Exhaled nitric oxide in premature and mature infants during the first months of life : Exhaled Nitric Oxide in neonates – a review ', Nitric Oxide-Biology and Chemistry, vol. 113-114, pp. 7-12 . https://doi.org/10.1016/j.niox.2021.04.005, Goth, F E M, Schmidt, B J, Agertoft, L & Jørgensen, I M 2021, ' Exhaled nitric oxide in premature and mature infants during the first months of life : Exhaled Nitric Oxide in neonates – a review ', Nitric oxide, vol. 113-114, pp. 7-12 . https://doi.org/10.1016/j.niox.2021.04.005
Accession number :
edsair.dedup.wf.001..2bffa46368340060530d75b02c791863

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