Influence of Anticoccidials on Oxidative Stress, Production Performance and Faecal Oocyst Counts in Broiler Chickens Infected with Eimeria Species

The influence of certain anticoccidial drugs on oxidative stress in broiler chickens infected with Eimeria species was assessed. There were two untreated (uninfected and infected), and three groups infected and treated with anticoccidials. The first treated group (Ro) was given robenidine, the 2nd a herbal anticoccidial (Herb) and the 3rd the combination of robenidine and the herbal anticoccidial (Ro+Herb). All infected groups were on day 14 challenged with oral inoculation of oocysts. The activities of catalase (CAT), superoxide dismutase (SOD) and glutathione S-transferase (GST), and the concentration of malondialdehyde (MDA) were estimated in blood taken on days 21 and 40. The oocyst numbers were calculated per gram, and chicken body weight and feed conversion ratio (FCR) measured. The activities of CAT, GST and the level of MDA were significantly lower (P