A Disposable Chip for the Collection of Quantitative Dried Blood Spot Samples

This work presents a disposable chip for metering and transferring an exactly defined liquid volume into a paper matrix using self-actuated dissolvable valves. Once a liquid droplet of 20-50 μl is applied to the chip, a volume of 1 μl is automatically metered, separated from the applied volume and subsequently transferred into conventional Whatman 903 paper used in Dried Blood Spot (DBS) sampling. QC 20140619