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Epstein-Barr virus in oral proliferative verrucous leukoplakia and squamous cell carcinoma : a preliminary study
- Source :
- Bagán Sebastián, José Vicente ; Jiménez Soriano, Yolanda ; Murillo Cortés, Judith ; Poveda Roda, Rafael ; Díaz Fernández, José María ; Gavaldá Esteve, Carmen ; Margaix Muñoz, María ; Scully, Crispian ; Alberola, Trinidad M. ; Torres Puente, Manuela ; Pérez Alonso, Manuel. Epstein-Barr virus in oral proliferative verrucous leukoplakia and squamous cell carcinoma : a preliminary study. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 13 2 2008: 5, RODERIC. Repositorio Institucional de la Universitat de Valéncia, instname, Scopus-Elsevier, Europe PubMed Central
- Publication Year :
- 2008
-
Abstract
- The aim of this study was to analyze proliferative verrucous leukoplakia (PVL) and oral squamous cell carcinoma (OSCC) for the possible presence of Epstein-Barr virus (EBV). We studied three groups: Sub-Group 1 was composed of 10 patients with PVL, (6 of whom had developed OSCC); Sub-Group 2 comprised 5 patients with OSCC but no preceding PVL; and Sub-Group 3 were 5 controls with clinically normal oral mucosa. Oral biopsies from all cases were examined for Epstein-Barr virus (EBV) by nested PCR. EBV was detected in 60% of Sub-Group 1 patients (PVL ) and in 40% of Sub-Group 2 (OSCC), but in 0% of SubGroup 3 (controls).
Details
- Database :
- OpenAIRE
- Journal :
- Bagán Sebastián, José Vicente ; Jiménez Soriano, Yolanda ; Murillo Cortés, Judith ; Poveda Roda, Rafael ; Díaz Fernández, José María ; Gavaldá Esteve, Carmen ; Margaix Muñoz, María ; Scully, Crispian ; Alberola, Trinidad M. ; Torres Puente, Manuela ; Pérez Alonso, Manuel. Epstein-Barr virus in oral proliferative verrucous leukoplakia and squamous cell carcinoma : a preliminary study. En: Medicina oral, patología oral y cirugía bucal. Ed. inglesa, 13 2 2008: 5, RODERIC. Repositorio Institucional de la Universitat de Valéncia, instname, Scopus-Elsevier, Europe PubMed Central
- Accession number :
- edsair.dedup.wf.001..081fee850b6d550ac647cb37a38b49e3