Improvement of the synthesis of immunologic carbohydrate vaccines containing the tumor associated antigen CaMBr1

Authors :: Panza, L
Poletti, L
PROSPERI, DAVIDE
Canevari, S
Perico, ME
Panza, L
Poletti, L
Prosperi, D
Canevari, S
Perico, M
Source :: European journal of organic chemistry, 22 (2001): 4331–4336., info:cnr-pdr/source/autori:Panza L., (1) Poletti L., (2) Prosperi D., (3) Canevari S., (2) Perico M.E. (2)/titolo:Improvement of the synthesis of immunologic carbohydrate vaccines containing the tumor associated antigen CaMBr1/doi:/rivista:European journal of organic chemistry (Print)/anno:2001/pagina_da:4331/pagina_a:4336/intervallo_pagine:4331–4336/volume:22
Publication Year :: 2001
Publisher :: Wiley-VCH-Verl., Weinheim , Germania, 2001.
Abstract: The simplified synthesis of a portion of Globo-H hexasaccharide, a saccharide antigen overexpressed by breast cancer cells, and its conjugation to two different immunogenic proteins are described. The conjugated vaccines, evaluated in a preclinical model, showed good immunogenic potential.

Subjects :: globo-H
immunologia
CHIM/06 - CHIMICA ORGANICA
MED/04 - PATOLOGIA GENERALE
carbohydrates
conjugate vaccine
antitumorali
CRM197
KLH
sintesi organica
BIO/10 - BIOCHIMICA
complex mixtures

Database :: OpenAIRE
Journal :: European journal of organic chemistry, 22 (2001): 4331–4336., info:cnr-pdr/source/autori:Panza L., (1) Poletti L., (2) Prosperi D., (3) Canevari S., (2) Perico M.E. (2)/titolo:Improvement of the synthesis of immunologic carbohydrate vaccines containing the tumor associated antigen CaMBr1/doi:/rivista:European journal of organic chemistry (Print)/anno:2001/pagina_da:4331/pagina_a:4336/intervallo_pagine:4331–4336/volume:22
Accession number :: edsair.dedup.wf.001..006cc166a82680d663ce3e57bf4f9ea4

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