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The plant hormone abscisic acid increases in human plasma after hyperglycemia and stimulates glucose consumption by adipocytes and myoblasts
- Source :
- The FASEB journal (2012)., info:cnr-pdr/source/autori:Bruzzone S, Ameri P, Briatore L, Mannino E, Basile G, Andraghetti G, Grozio A, Magnone M, Guida L, Scarfì S, Salis A, Damonte G, Sturla L, Nencioni A, Fenoglio D, Fiory F, Miele C, Beguinot F, Ruvolo V, Bormioli M, Colombo G, Maggi D, Murialdo G, Cordera/titolo:The plant hormone abscisic acid increases in human plasma after hyperglycemia and stimulates glucose consumption by adipocytes and myoblasts./doi:/rivista:The FASEB journal/anno:2012/pagina_da:/pagina_a:/intervallo_pagine:/volume
- Publication Year :
- 2012
- Publisher :
- Federation of American Societies for Experimental Biology, [Bethesda, Md.] , Stati Uniti d'America, 2012.
-
Abstract
- The plant hormone abscisic acid (ABA) is released from glucose-challenged human pancreatic ² cells and stimulates insulin secretion. We investigated whether plasma ABA increased during oral and intravenous glucose tolerance tests (OGTTs and IVGTTs) in healthy human subjects. In all subjects undergoing OGTTs (n=8), plasma ABA increased over basal values (in a range from 2- to 9-fold). A positive correlation was found between the ABA area under the curve (AUC) and the glucose AUC. In 4 out of 6 IVGTTs, little or no increase of ABA levels was observed. In the remaining subjects, the ABA increase was similar to that recorded during OGTTs. GLP-1 stimulated ABA release from an insulinoma cell line and from human islets, by
- Subjects :
- fungi
food and beverages
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- The FASEB journal (2012)., info:cnr-pdr/source/autori:Bruzzone S, Ameri P, Briatore L, Mannino E, Basile G, Andraghetti G, Grozio A, Magnone M, Guida L, Scarfì S, Salis A, Damonte G, Sturla L, Nencioni A, Fenoglio D, Fiory F, Miele C, Beguinot F, Ruvolo V, Bormioli M, Colombo G, Maggi D, Murialdo G, Cordera/titolo:The plant hormone abscisic acid increases in human plasma after hyperglycemia and stimulates glucose consumption by adipocytes and myoblasts./doi:/rivista:The FASEB journal/anno:2012/pagina_da:/pagina_a:/intervallo_pagine:/volume
- Accession number :
- edsair.cnr...........534283006e699dc2f58002efd39ff7df