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Genetic variation in CCR2 and CXCL12 genes impacts on CD4 restoration in patients initiating cART with advanced immunesupression

Authors :
Restrepo C
Gutierrez-Rivas M
Pacheco YM
García M
Blanco J
Medrano LM
Navarrete-Muñoz MA
Gutiérrez F
Miralles P
Dalmau D
Gómez JL
Górgolas M
Cabello A
Resino S
Benito JM
Rallón N
Source :
PLoS One, r-FISABIO. Repositorio Institucional de Producción Científica, instname
Publication Year :
2019
Publisher :
PUBLIC LIBRARY SCIENCE, 2019.

Abstract

Objective We investigated the association of genetic polymorphisms in chemokine and chemokine receptor genes with poor immunological recovery in HIV patients starting combined antiretroviral therapy (cART) with low CD4 T-cell counts. Methods A case-control study was conducted in 412 HIV-infected patients starting cART with CD4 T-cell count

Details

ISSN :
19326203
Database :
OpenAIRE
Journal :
PLoS One, r-FISABIO. Repositorio Institucional de Producción Científica, instname
Accession number :
edsair.RECOLECTA.....61a4b1f5784e5d0df318720b2d6ee4df