Transkardijalni gradijenti IL6, TNFa i adiponektina u kardiovaskularnih bolesnika

Adiponectin (ADIPOQ), protein produced by adipose cells, has antiatherogenic effect while interleukin 6 (IL6) and tumor necrosis factor (TNFa) have proinflamatory and proatherogenic effects. Aim of this study was to determine concentrations of ADIPOQ, IL6 and TNFa in aortic root (AR) and coronary sinus (CS) along with transcardiac gradients (TG), concentration ratio of coronary sinus to aortic root, in CAD patients. TG can indicate for values above 1 decrease or absence of utilization or existence of source throughout heart.