@b-2-microglobulin-associated nodular amyloidosis of the tongue

The tongue is an uncommon site for the deposition of @b-2-microglobulin amyloid. A case is presented of nodular amyloidosis of the tongue in a patient having prolonged hemodialysis. The lesions were small, firm, yellowish nodules on the lateral aspect of the tongue and were shown to be deposits of @b-2-microglobulin amyloid. The pathogenesis and differential diagnosis are discussed.