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Elevated Topoisomerase I Activity in Cervical Cancer as a Target for Chemoradiation Therapy

Authors :
Chen, Bing-Mae
Chen, Jia-Yi
Kao, Marine
Lin, Jia-Bo
Yu, Mu-Hsien
Roffler, Steve R.
Source :
Gynecologic Oncology; November 2000, Vol. 79 Issue: 2 p272-280, 9p
Publication Year :
2000

Abstract

Objective.The aim of this study was to determine whether the activity of topoisomerase I (topo I), the target of the anti-neoplastic drug camptothecin (CPT), is elevated in cervical cancer and whether CPT can radiosensitize cervical tumors.

Details

Language :
English
ISSN :
00908258 and 10956859
Volume :
79
Issue :
2
Database :
Supplemental Index
Journal :
Gynecologic Oncology
Publication Type :
Periodical
Accession number :
ejs835661
Full Text :
https://doi.org/10.1006/gyno.2000.5947