Back to Search
Start Over
Natural Human Antibody Responses to Plasmodium vivax Apical Membrane Antigen 1 under Low Transmission and Unstable Malaria Conditions in Sri Lanka
- Source :
- Infection and Immunity; January 2006, Vol. 74 Issue: 1 p798-801, 4p
- Publication Year :
- 2006
-
Abstract
- Plasmodium vivax apical membrane antigen 1, an important malaria vaccine candidate, was immunogenic during natural malaria infections in Sri Lanka, where low transmission and unstable malaria conditions prevail. Antibody prevalence increased with exposure in areas where malaria was or was not endemic. A marked isotype switch to cytophilic (immunoglobulin G1 [IgG1]/IgG3) antibodies was evident with increasing exposure exclusively in residents from areas of endemicity.
Details
- Language :
- English
- ISSN :
- 00199567 and 10985522
- Volume :
- 74
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- Infection and Immunity
- Publication Type :
- Periodical
- Accession number :
- ejs8238972