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A Practical Method for the Synthesis of a Cyclosporine−Fluorescein Conjugate
- Source :
- Organic Process Research & Development; November 2005, Vol. 9 Issue: 6 p822-824, 3p
- Publication Year :
- 2005
-
Abstract
- A straightforward synthesis of a cyclosporine−fluorescein conjugate through the MeBmt hydroxyl group was developed. Reaction of cyclosporine A in phosgene/toluene solution with added triethylamine, followed by subsequent reaction with 4-aminomethylfluorescein, produces good yields of the cyclosporine−fluorescein conjugate.
Details
- Language :
- English
- ISSN :
- 10836160 and 1520586X
- Volume :
- 9
- Issue :
- 6
- Database :
- Supplemental Index
- Journal :
- Organic Process Research & Development
- Publication Type :
- Periodical
- Accession number :
- ejs8150325