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Evaluation of Clonorchis sinensisRecombinant 7-Kilodalton Antigen for Serodiagnosis of Clonorchiasis

Authors :
Zhao, Qin-Ping
Moon, Sung-Ung
Lee, Hyeong-Woo
Na, Byoung-Kuk
Cho, Seung-Yull
Kong, Yoon
Jiang, Ming-Sen
Li, Ai-Hua
Kim, Tong-Soo
Source :
Clinical and Vaccine Immunology (formerly CDLI); July 2004, Vol. 11 Issue: 4 p814-817, 4p
Publication Year :
2004

Abstract

ABSTRACTThe diagnostic applicability of the Clonorchis sinensisrecombinant 7-kDa protein was evaluated. In enzyme-linked immunosorbent assays and immunoblots, the protein showed high sensitivities (81.3 and 71.9%, respectively) and specificities (92.6 and 89.7%, respectively) for sera obtained from various helminthic infections. Some paragonimiasis sera showed cross-reactions. The antigen might be valuable in the serodiagnosis of human clonorchiasis.

Details

Language :
English
ISSN :
15566811 and 1556679X
Volume :
11
Issue :
4
Database :
Supplemental Index
Journal :
Clinical and Vaccine Immunology (formerly CDLI)
Publication Type :
Periodical
Accession number :
ejs7841900
Full Text :
https://doi.org/10.1128/CDLI.11.4.814-817.2004