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Duration of sample storage dramatically alters expression of the human immunodeficiency virus coreceptors CXCR4 and CCR5.
- Source :
- Clinical and Vaccine Immunology (formerly CDLI); March 2001, Vol. 8 Issue: 2 p432-6, 5p
- Publication Year :
- 2001
-
Abstract
- Expression of the chemokine receptors CXCR4 and CCR5 was monitored using EDTA-anticoagulated whole blood held for different time periods prior to fluorescent-antibody staining. When left overnight CXCR4 expression on leukocytes was substantially increased, whereas CCR5 expression was reduced. The results were similar when heparin and acid-citrate-dextrose were used as anticoagulants.
Details
- Language :
- English
- ISSN :
- 15566811 and 1556679X
- Volume :
- 8
- Issue :
- 2
- Database :
- Supplemental Index
- Journal :
- Clinical and Vaccine Immunology (formerly CDLI)
- Publication Type :
- Periodical
- Accession number :
- ejs7840618
- Full Text :
- https://doi.org/10.1128/CDLI.8.2.432-436.2001