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Δ-cis-α-[Ru(RR-picchxnMe2 )(phen)]2+ shows minor groove AT selectivity with oligonucleotides

Authors :
M. Proudfoot, Emma
P. Mackay, Joel
S. Vagg, Robert
A. Vickery, Kymberley
A. Williams, Peter
Karuso, Peter
Source :
Chemical Communications; September 7, 1997, Vol. 1997 Issue: 17 p1623-1624, 2p
Publication Year :
1997

Abstract

NMR studies show that the ternary octahedral Δ-cis-α- [Ru(RR-picchxnMe2)(phen)]2+ cation binds with AT selectivity in the minor groove of [d(CGCGATCGCG)2] and [d(ATATCGATAT)2] duplexes through a non-intercalative interaction.

Details

Language :
English
ISSN :
13597345 and 1364548X
Volume :
1997
Issue :
17
Database :
Supplemental Index
Journal :
Chemical Communications
Publication Type :
Periodical
Accession number :
ejs7740276
Full Text :
https://doi.org/10.1039/a704001f