Carbonate-containing hydroxyapatite derived from calcium tripolyphosphate gel with urea

Abstract Carbonate containing hydroxyapatite (CO3HAp) is one of the candidate materials as a bioresorbable bone substitute. In the present work, CO3HAp was efficiently prepared by a hydrothermal treatment of calcium tripolyphosphate gel with urea at 140 °C for 24 h. Chemical potential plots of the CO3HAp for estimation of its dissolution behavior suggested that the CO3HAp is more soluble than hydroxyapatite (HAp) and is as soluble as octacalcium phosphate (OCP) and/or ß -tricalcium phosphate (TCP). This material is expected to be applied to bioresorbable materials such as bone fillers.