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Oxidation of Low Molecular Weight Chloroalkanes by Cytochrome P450<SUB>CAM</SUB>

Authors :
Lefever, M.R.
Wackett, L.P.
Source :
Biochemical and Biophysical Research Communications; May 30, 1994, Vol. 201 Issue: 1 p373-378, 6p
Publication Year :
1994

Abstract

Cytochrome P450&lt;SUB&gt;CAM&lt;/SUB&gt; from Pseudomonas putida G786 oxidized chlorinated ethanes and 1,2-dichloropropane. The rate of NADH oxidation decreased with decreasing chlorine substitution. The single detectable oxidation products of 1,1,1-trichloroethane and 1,2-dichloropropane were 1,1,1-trichloroethanol and chloroacetone, respectively. Organic product formation was largely uncoupled from NADH oxidation.Copyright 1994, 1999 Academic Press, Inc.

Details

Language :
English
ISSN :
0006291X and 10902104
Volume :
201
Issue :
1
Database :
Supplemental Index
Journal :
Biochemical and Biophysical Research Communications
Publication Type :
Periodical
Accession number :
ejs722238
Full Text :
https://doi.org/10.1006/bbrc.1994.1711