Circulating Stress Hormones, Brain Health, and Cognition in Healthy Older Adults: Cross-Sectional Findings and Sex Differences in the Age-Well Clinical Trial

Authors :: Liebscher, Maxie
White, Silke
Hass, Simon
Chocat, Anne
Mezenge, Florence
Landeau, Brigitte
Delarue, Marion
Hébert, Oriane
Turpin, Anne-Laure
Marchant, Natalie L.
Chételat, Gaël
Klimecki, Olga
Poisnel, Géraldine
Wirth, Miranka
André, Claire
Champetier, Pierre
Chauveau, Léa
Collette, Fabienne
Dautricourt, Sophie
de Flores, Robin
De La Sayette, Vincent
Demnitz-King, Harriet
Fauvel, Séverine
Felisatti, Francesca
Ferment, Victor
Ferrand-Devouge, Eglantine
Gonneaud, Julie
Garnier-Crussard, Antoine
Hamel, Anaïs
Haudry, Sacha
Krolak-Salmon, Pierre
Kuhn, Elizabeth
Lefranc, Valérie
Lutz, Antoine
Ourry, Valentin
Palix, Cassandre
Quillard, Anne
Rauchs, Géraldine
Salmon, Eric
Touron, Edelweiss
Vuilleumier, Patrik
Whitfield, Tim
Source :: Biological Psychiatry Global Open Science; 20250101, Issue: Preprints
Publication Year :: 2025
Abstract: Increased stress is a proposed risk factor for Alzheimer’s disease (AD). We examined cross-sectional associations between circulating stress biomarkers and multimodal measures of brain health and cognitive susceptibility to AD in older adults and sex-specific subgroups.

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