Clinical and genetic diagnosis of familial hypercholesterolaemia in patients undergoing coronary angiography: the Ludwigshafen Risk and Cardiovascular Health Study

Graphical AbstractDiagnosis rates of familial hypercholesterolaemia with different clinical criteria and with genetic testing (left panel) and receiver operating characteristic curves for diagnostic scores with genetic diagnosis as reference (right panel). FH, familial hypercholesterolaemia; AUC, area under the curve; LDL-C, low-density lipoprotein cholesterol; FAMCAT, familial hypercholesterolaemia case ascertainment tool; DLCN, Dutch Lipid Clinical Network; ROC, receiver operating characteristic.