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Local Single-dose Teriparatide for BRONJ Prevention: An Animal Study

Authors :
Etemadi, Milad
Sehat, Mohammad Soroush
Teimoori, Farshad
Razavi, Seyed Mohammad
Tajmiri, Golnaz
Source :
International Dental Journal; October 2024, Vol. 74 Issue: 1, Number 1 Supplement 1 pS65-S65, 1p
Publication Year :
2024

Abstract

The uncertain prognosis of bisphosphonate-related osteonecrosis of the jaw (BRONJ) has sparked interest in preventive approaches, notably using teriparatide, a recombinant human parathyroid hormone fragment. Given teriparatide's confirmed systemic efficacy, this study investigates its impact through single local dose administration on MRONJ prevention in a rat model.

Details

Language :
English
ISSN :
00206539 and 1875595X
Volume :
74
Issue :
1, Number 1 Supplement 1
Database :
Supplemental Index
Journal :
International Dental Journal
Publication Type :
Periodical
Accession number :
ejs67706557
Full Text :
https://doi.org/10.1016/j.identj.2024.07.767