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Targeting T cells with tetravalent bispecific antibodies for the treatment of graft-versus-host disease

Authors :
Espinosa-Cotton, Madelyn
Hoseini, Sayed Shahabuddin
Miranda, Ileana C.
Herrick, John
Cheung, Nai-Kong V.
Source :
Blood Advances; January 2025, Vol. 9 Issue: 1 p116-126, 11p
Publication Year :
2025

Abstract

•CD3×CD3 tetravalent antibodies cure GVHD in xenogeneic mouse models and warrant further investigation in more clinically relevant models.

Details

Language :
English
ISSN :
24739529 and 24739537
Volume :
9
Issue :
1
Database :
Supplemental Index
Journal :
Blood Advances
Publication Type :
Periodical
Accession number :
ejs67448527
Full Text :
https://doi.org/10.1182/bloodadvances.2022009187