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Diagnostic potential of combining plasma biomarkers of tissue damage and inflammation in pediatric TB

Authors :
López-Suárez, Andrea
Santos-Sebastián, Mar
Hernanz-Lobo, Alicia
Rincón-López, Elena
Aguilera-Alonso, David
Saavedra-Lozano, Jesús
Ruiz Serrano, María Jesús
Hernández-Bartolomé, Ángel
Medrano de Dios, Luz María
Jiménez Fuentes, José Luis
Navarro, María Luisa
Tebruegge, Marc
Santiago-García, Begoña
Source :
Journal of Microbiology, Immunology and Infection; 20240101, Issue: Preprints
Publication Year :
2024

Abstract

Immune-based diagnostic tests for tuberculosis (TB) have suboptimal sensitivity in children and cannot differentiate between latent infection (LTBI) and active disease. This study evaluated the diagnostic potential of a broad range of biomarkers of tissue damage and inflammation in unstimulated plasma in children.

Details

Language :
English
ISSN :
16841182
Issue :
Preprints
Database :
Supplemental Index
Journal :
Journal of Microbiology, Immunology and Infection
Publication Type :
Periodical
Accession number :
ejs67334690
Full Text :
https://doi.org/10.1016/j.jmii.2024.07.011