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(2 + 2 + 1)-Cyclization of Glycine Derivatives with Alkenes and CO2

Authors :
Ye, Youwan
Huo, Congde
Source :
Organic Letters; September 2024, Vol. 26 Issue: 37 p7897-7901, 5p
Publication Year :
2024

Abstract

A highly atom-economic (2 + 2 + 1)-cyclization of glycine derivatives with alkenes and CO2facilitated by visible light catalysis is described. A range of multisubstituted pyrrolidones were synthesized under simple and mild reaction conditions. A reasonable mechanism involving redox-neutral radical-polar crossover is proposed.

Details

Language :
English
ISSN :
15237060 and 15237052
Volume :
26
Issue :
37
Database :
Supplemental Index
Journal :
Organic Letters
Publication Type :
Periodical
Accession number :
ejs67333411
Full Text :
https://doi.org/10.1021/acs.orglett.4c02805