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Synthesis of Functionalized Oxacalix[4]arenes

Authors :
Katz, J. L.
Feldman, M. B.
Conry, R. R.
Source :
Organic Letters; January 2005, Vol. 7 Issue: 1 p91-94, 4p
Publication Year :
2005

Abstract

<UFIGR ID="ol047840tn00001">Tetranitrooxacalix[4]arenes are generated in high yield by the room-temperature S<INF>N</INF>Ar reaction of 1,3-dihydroxybenzenes with 1,5-difluoro-2,4-dinitrobenzene. The reaction is tolerant to a range of functionality on the nucleophilic component, including hydroxyl-substitution at the 2- and 5-positions, which yields previously unknown 26,28- and 5,17-dihydroxyoxacalix[4]arenes.

Details

Language :
English
ISSN :
15237060 and 15237052
Volume :
7
Issue :
1
Database :
Supplemental Index
Journal :
Organic Letters
Publication Type :
Periodical
Accession number :
ejs6719318