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Glutamine withdrawal leads to the preferential activation of lipid metabolism in metastatic colorectal cancer
- Source :
- Translational Oncology; 20240101, Issue: Preprints
- Publication Year :
- 2024
-
Abstract
- •Glutamine is differentially metabolized in primary versus metastatic tumors.•A three gene glutamine metabolism signature could predict prognosis.•Metastatic SW620 cells increased lipid uptake upon glutamine starvation.•Glutamine starvation led to increased motility in SW620 cells
Details
- Language :
- English
- ISSN :
- 19447124 and 19365233
- Issue :
- Preprints
- Database :
- Supplemental Index
- Journal :
- Translational Oncology
- Publication Type :
- Periodical
- Accession number :
- ejs67066690
- Full Text :
- https://doi.org/10.1016/j.tranon.2024.102078