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Influence of TP53gene mutations and their allelic status in myelodysplastic syndromes with isolated 5q deletion
- Source :
- Blood; October 2024, Vol. 144 Issue: 16 p1722-1731, 10p
- Publication Year :
- 2024
-
Abstract
- •TP53allelic state and VAF significantly correlates with outcomes in patients with MDS-del(5q).•Based on TP53allelic status and a VAF cutoff of 20%, 2 distinct groups with clinical implications are identified among MDS-del(5q).
Details
- Language :
- English
- ISSN :
- 00064971 and 15280020
- Volume :
- 144
- Issue :
- 16
- Database :
- Supplemental Index
- Journal :
- Blood
- Publication Type :
- Periodical
- Accession number :
- ejs67043037
- Full Text :
- https://doi.org/10.1182/blood.2024023840