Back to Search Start Over

Losartan Treatment Reduces Esophageal Eosinophilic Inflammation in a Subset of Eosinophilic Esophagitis

Authors :
Abonia, J. Pablo
Rudman Spergel, Amanda K.
Hirano, Ikuo
Shoda, Tetsuo
Zhang, Xue
Martin, Lisa J.
Mukkada, Vincent A.
Putnam, Philip E.
Blacklidge, Melodie
Neilson, Derek
Collins, Margaret H.
Yang, Guang-Yu
Capocelli, Kelley E.
Foote, Heather
Eby, Mike
Dong, Stephanie
Aceves, Seema S.
Rothenberg, Marc E.
Wechsler, Joshua
Davis, Carla
Furuta, Glenn
Khoury, Paneez
Gupta, Sandeep K.
Spergel, Jonathan
Leung, John
Menard-Katcher, Paul
Falk, Gary
Gonsalves, Nirmala Prabu
Peterson, Kathryn
Source :
The Journal of Allergy and Clinical Immunology: In Practice; September 2024, Vol. 12 Issue: 9 p2427-2438.e3
Publication Year :
2024

Abstract

Eosinophilic esophagitis (EoE) is a chronic, food antigen–driven esophageal disorder. Connective tissue disorders (CTDs) and esophageal connective tissue alterations are associated with EoE. Therefore, angiotensin II type 1 receptor blockade with losartan, an accepted CTD treatment, is a potential EoE treatment.

Details

Language :
English
ISSN :
22132198
Volume :
12
Issue :
9
Database :
Supplemental Index
Journal :
The Journal of Allergy and Clinical Immunology: In Practice
Publication Type :
Periodical
Accession number :
ejs67002036
Full Text :
https://doi.org/10.1016/j.jaip.2024.07.011