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T-Cell Responses Against Mycobacterium ulceransand Mycobacterium tuberculosisProtein Extracts Identify Children With Buruli Ulcer Disease
- Source :
- Journal of the Pediatric Infectious Diseases Society; December 2022, Vol. 11 Issue: 12 p575-577, 3p
- Publication Year :
- 2022
-
Abstract
- Immune-based diagnosis of Buruli ulcer disease (BUD) in children is difficult due to cross-reactivity between mycobacteria. We found that T-cell IFNγ/TNFα responses against Mycobacterium(M.) ulceransand M. tuberculosis(PPDMulc, PPDMtub) were different between children with BUD (n= 27) and TB (n= 20) but only ratios (PPDMtub/PPDMulc) discriminated the study groups efficiently.
Details
- Language :
- English
- ISSN :
- 20487193 and 20487207
- Volume :
- 11
- Issue :
- 12
- Database :
- Supplemental Index
- Journal :
- Journal of the Pediatric Infectious Diseases Society
- Publication Type :
- Periodical
- Accession number :
- ejs66923128
- Full Text :
- https://doi.org/10.1093/jpids/piac092