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Consolidation with First and Second Allogeneic Transplants in Adults with Relapsed/Refractory B-ALL Following Response to CD19CAR T Cell Therapy

Authors :
Aldoss, Ibrahim
Shan, Haoyue
Yang, Dongyun
Clark, Mary C.
Al Malki, Monzr
Aribi, Ahmed
Agrawal, Vaibhav
Sandhu, Karamjeet
Salhotra, Amandeep
Pourhassan, Hoda
Koller, Paul
Ali, Haris
Artz, Andrew
Karras, Nicole
Pawlowska, Anna B.
Murphy, Lindsey
Palmer, Joycelynne
Stein, Anthony
Marcucci, Guido
Pullarkat, Vinod
Nakamura, Ryotaro
Forman, Stephen J.
Source :
Transplantation and Cellular Therapy; August 2024, Vol. 30 Issue: 8 p788.e1-788.e9, 9p
Publication Year :
2024

Abstract

•AlloHCT post CAR-T response is feasible and associated with low early NRM.•AlloHCT outcomes in CAR-T responders were encouraging in high-risk r/r B-ALL.•Encouraging outcomes extend to CAR-T responders undergoing second transplant.

Details

Language :
English
ISSN :
26666375 and 26666367
Volume :
30
Issue :
8
Database :
Supplemental Index
Journal :
Transplantation and Cellular Therapy
Publication Type :
Periodical
Accession number :
ejs66631224
Full Text :
https://doi.org/10.1016/j.jtct.2024.06.013