Back to Search
Start Over
Genomic Determinants Associated with Modes of Progression and Patterns of Failure in Metachronous Oligometastatic Castration-sensitive Prostate Cancer
- Source :
- European Urology Oncology; 20240101, Issue: Preprints
- Publication Year :
- 2024
-
Abstract
- For patients with metachronous oligometastatic castration-sensitive prostate cancer, tumor genomics may play a role in the mode of progression and pattern of failure after initial therapy for metastatic disease. Specifically, patients with TP53and RB1mutations have a higher likelihood of progression, and TP53, SPOP, and WNT pathway mutations may have a role in metastatic organotropism directing the likelihood of bone and visceral disease progression.
Details
- Language :
- English
- ISSN :
- 25889311
- Issue :
- Preprints
- Database :
- Supplemental Index
- Journal :
- European Urology Oncology
- Publication Type :
- Periodical
- Accession number :
- ejs66527327
- Full Text :
- https://doi.org/10.1016/j.euo.2024.05.011