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Impact of Xpert MTB/RIF implementation in tuberculosis case detection and control in Brazil: a nationwide intervention time-series analysis (2011–2022)

Authors :
Villalva-Serra, Klauss
Barreto-Duarte, Beatriz
Miguez-Pinto, João P.
Queiroz, Artur T.L.
Rodrigues, Moreno M.
Rebeiro, Peter F.
Amorim, Gustavo
Cordeiro-Santos, Marcelo
Sterling, Timothy R.
Araújo-Pereira, Mariana
Andrade, Bruno B.
Source :
The Lancet Regional Health - Americas; 20240101, Issue: Preprints
Publication Year :
2024

Abstract

Since 2014, Brazil has gradually implemented the Xpert MTB/RIF (Xpert) test to enhance early tuberculosis (TB) and drug-resistant (DR-TB) detection and control, yet its nationwide impact remains underexplored. Our study conducts an intervention time-series analysis (ITSA) to evaluate how the Xpert's implementation has improved TB and DR-TB detection nationwide.

Details

Language :
English
ISSN :
2667193X
Issue :
Preprints
Database :
Supplemental Index
Journal :
The Lancet Regional Health - Americas
Publication Type :
Periodical
Accession number :
ejs66499330
Full Text :
https://doi.org/10.1016/j.lana.2024.100804