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CD8+T-cell differentiation and dysfunction inform treatment response in acute myeloid leukemia
- Source :
- Blood; September 2024, Vol. 144 Issue: 11 p1168-1182, 15p
- Publication Year :
- 2024
-
Abstract
- •Bone marrow CD8+T-cell differentiation states play a crucial role in patients with AML response to therapy.•Single-cell RNA sequencing analysis reveals developmental dichotomic programs and clonal expansion in relation to therapy response in AML.
Details
- Language :
- English
- ISSN :
- 00064971 and 15280020
- Volume :
- 144
- Issue :
- 11
- Database :
- Supplemental Index
- Journal :
- Blood
- Publication Type :
- Periodical
- Accession number :
- ejs66465992
- Full Text :
- https://doi.org/10.1182/blood.2023021680