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The oxygenation of cholesterol esters by the reticulocyte lipoxygenase

Authors :
Belkner, Jutta
Wiesner, Rainer
Kühn, Hartmut
Lankin, Vadim Z.
Source :
FEBS Letters; January 1991, Vol. 279 Issue: 1 p110-114, 5p
Publication Year :
1991

Abstract

The arachidonate 15-lipoxygenase from rabbit reticulocytes oxygenates cholesterol esters containing polyenoic fatty acids. Cholesterol esterified with saturated fatty acids is not oxygenated. The structures of the oxygenation products formed from various cholesterol esters have been identified by high pressure liquid chromatography, UV-spectroscopy and gas chromatography/mass spectroscopy. Oxygenated cholesterol esters have been detected in atherosclerotic plaques of human aortas.

Details

Language :
English
ISSN :
00145793
Volume :
279
Issue :
1
Database :
Supplemental Index
Journal :
FEBS Letters
Publication Type :
Periodical
Accession number :
ejs66322339
Full Text :
https://doi.org/10.1016/0014-5793(91)80263-3