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Intramuscular administration of tranexamic acid in a large swine model of hemorrhage with hyperfibrinolysis
- Source :
- Journal of Trauma and Acute Care Surgery; May 2024, Vol. 96 Issue: 5 p735-741, 7p
- Publication Year :
- 2024
-
Abstract
- Hemorrhage accounts for 40-50% of deaths in severe trauma patients. IV administration of TXA within three hours of injury reduces mortality. In this study we show IM TXA is equally efficacious as IV in treating hyperfibrinolysis in an in vivo swine model.
Details
- Language :
- English
- ISSN :
- 21630755 and 21630763
- Volume :
- 96
- Issue :
- 5
- Database :
- Supplemental Index
- Journal :
- Journal of Trauma and Acute Care Surgery
- Publication Type :
- Periodical
- Accession number :
- ejs66201923
- Full Text :
- https://doi.org/10.1097/TA.0000000000004207