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Hemojuvelin mediated hepcidin induction requires both bone morphogenetic protein type I receptors ALK2 and ALK3

Hemojuvelin mediated hepcidin induction requires both bone morphogenetic protein type I receptors ALK2 and ALK3

Authors :
Dogan, Deniz Y.
Urzica, Eugen I.
Hornung, Isabelle
Kastl, Philipp
Oguama, David
Fette, Franca M.
Nguyen, Lien H.
Rosenbauer, Frank
Zacharowski, Kai
Klingmüller, Ursula
Gradhand, Elise
Von Knethen, Andreas
Popp, Rüdiger
Fleming, Ingrid
Schrader, Lisa
Steinbicker, Andrea U.
Source :
Blood Advances; 20240101, Issue: Preprints
Publication Year :
2024

Abstract

•The bone morphogenetic protein type I receptors ALK2 and ALK3 are required for HJV- mediated induction of hepcidin in vivo.

Details

Language :
English
ISSN :
24739529 and 24739537
Issue :
Preprints
Database :
Supplemental Index
Journal :
Blood Advances
Publication Type :
Periodical
Accession number :
ejs66020903
Full Text :
https://doi.org/10.1182/bloodadvances.2023012322