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Exacerbation of thrombo-inflammation by JAK2V617Fmutation worsens the prognosis of cerebral venous sinus thrombosis

Authors :
Bourrienne, Marie-Charlotte
Le Cam Duchez, Véronique
Faille, Dorothée
Farkh, Carine
Solonomenjanahary, Mialitiana
Gay, Juliette
Loyau, Stéphane
Journé, Clément
Dupont, Sébastien
Ollivier, Véronique
Villeval, Jean-Luc
Plo, Isabelle
Edmond, Valérie
Jandrot-Perrus, Martine
Labrouche-Colomer, Sylvie
Cassinat, Bruno
Verger, Emmanuelle
Desilles, Jean-Philippe
Ho-Tin-Noé, Benoît
Bagan, Aude Triquenot
Mazighi, Mikaël
Ajzenberg, Nadine
Source :
Blood Advances; 20240101, Issue: Preprints
Publication Year :
2024

Abstract

•JAK2V617Fmutation contributes to hemorrhagic lesions and to mortality in an experimental model of cerebral venous thrombosis•JAK2V617Fmutation exacerbates thrombo-inflammatory response during cerebral venous thrombosis

Details

Language :
English
ISSN :
24739529 and 24739537
Issue :
Preprints
Database :
Supplemental Index
Journal :
Blood Advances
Publication Type :
Periodical
Accession number :
ejs65703674
Full Text :
https://doi.org/10.1182/bloodadvances.2023011692