Evaluation of the hepatoprotective effect of an hydroalcoholic extract of Jatropha dioicaagainst the damage induced by valproic acid in Wistar rats

Liver diseases have gained importance due to their prevalence, incidence and because most chronic liver diseases have no cure, except for hepatitis C. Liver damage induced by drugs such as valproic acid (VPA) has been used to study therapeutic alternatives. Jatropha dioicamay be one of these alternatives as it has metabolites with potential antioxidant activity. The objetive of this study was to evaluate the hepatoprotective effect of a hydroalcoholic extract of J. dioicaagainst VPA-induced damage in Wistar rats.