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An adult with recurrent atypical teratoid rhabdoid tumor of the spine
- Source :
- CNS Oncology; March 2024, Vol. 13 Issue: 1
- Publication Year :
- 2024
-
Abstract
- Atypical teratoid rhabdoid tumors (AT/RT) are rare and highly malignant CNS neoplasms primarily affecting children. Adult cases are extremely uncommon, with only approximately 92 reported. Spinal AT/RT in adults is particularly rare. Here, we present the case of a 50-year-old patient diagnosed with AT/RT of the spine. Initially, they were diagnosed and treated for a spinal ependymoma. However, after 10 years, a recurrence was detected through magnetic resonance imaging (MRI) and the tumor was reclassified as AT/RT. We discuss the significance of SMARCB1gene mutations in diagnosing AT/RT and describe our unique treatment approach involving surgery, radiation and anti-PD1 therapy in this patient.
Details
- Language :
- English
- ISSN :
- 20450907 and 20450915
- Volume :
- 13
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- CNS Oncology
- Publication Type :
- Periodical
- Accession number :
- ejs65529804
- Full Text :
- https://doi.org/10.2217/cns-2023-0017