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Temperature stability of urinary F2-isoprostane and 8-hydroxy-2′-deoxyguanosine

Authors :
Kordas, Katarzyna
Ghazal, Diala
Queirolo, Elena I.
Olson, James R.
Beledo, María Inés
Browne, Richard W.
Source :
Practical Laboratory Medicine; March 2024, Vol. 39 Issue: 1
Publication Year :
2024

Abstract

Clinical and epidemiological studies employ long-term temperature storage but the effect of temperature on the stability of oxidative stress (OS) markers is unknown. We investigated the effects of storage at −20 °C and −80 °C over 4–9 months on F2-isoprostanes (F2-IsoP) and 8-hydroxy-2′-deoxyguanosine (8-OHdG) levels in urine of children, a population group among whom the measurement of these markers is still limited.

Details

Language :
English
ISSN :
23525517
Volume :
39
Issue :
1
Database :
Supplemental Index
Journal :
Practical Laboratory Medicine
Publication Type :
Periodical
Accession number :
ejs65514768
Full Text :
https://doi.org/10.1016/j.plabm.2024.e00373