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A Completely Oral Regimen Including Oral Etoposide As Cytoreductive Chemotherapy Combined with All Trans Retinoic Acid and Oral Arsenic for Induction Therapy in Patients with High-Risk APL:Comparable to Intravenous Cytoreductive Therapy

Authors :
Tang, Feifei
Duan, Wen-Bing
Liu, Xiao-Hong
Lu, Sheng-Ye
Zhao, Xiao-Su
Qin, Ya-Zhen
Jia, Jin-Song
Wang, Jing
Gong, Li-Zhong
Jiang, Qian
Ting, Zhao
Shi, Hong-Xia
Chang, Ying-Jun
Huang, Xiao-Jun
Jiang, Hao
Source :
Blood; November 2023, Vol. 142 Issue: 1, Number 1 Supplement 1 p4288-4288, 1p
Publication Year :
2023

Abstract

Background :Under the pandemic of coronavirus disease 2019 (COVID-19), in addition to all trans retinoic acid (ATRA) and oral arsenic(RIF), high-risk acute promyelocytic leukemia (APL) patients might lack of the necessity of intravenous cytotoxic chemotherapy infusions timely. Therefore, there is an urgent need for an oral, efficient and safe regimen for high-risk APL.

Details

Language :
English
ISSN :
00064971 and 15280020
Volume :
142
Issue :
1, Number 1 Supplement 1
Database :
Supplemental Index
Journal :
Blood
Publication Type :
Periodical
Accession number :
ejs64705469
Full Text :
https://doi.org/10.1182/blood-2023-188657