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Fertility and Pregnancy in Patients with Congenital Neutropenia: Experience of the French Severe Chronic Neutropenia Registry in 565 Patients Above Age of 15 Years

Authors :
Alimi, Aurelia
Nika, Evrard
Beaupain, Blandine
Fieschi, Claire
Sicre De Fontbrune, Flore
Aladjidi, Nathalie
Moshous, Despina
Moignet.Autrel, Aline
Mallebranche, Coralie
Biosse Duplan, Martin
Bellanne-Chantelot, Christine
Donadieu, Jean
Source :
Blood; November 2023, Vol. 142 Issue: 1, Number 1 Supplement 1 p2545-2545, 1p
Publication Year :
2023

Abstract

Congenital neutropenia (CN) are characterized by chronic neutropenia with frequent co-morbidities. Approximately 30 different entities have been described with various clinical phenotypes and genotypes (PMID: 28875503). As survival rates and life expectancy improve, fertility and pregnancies becomes a common issue. Only one study had addressed this question, reporting 38 pregnancies in women with idiopathic neutropenia (n=6) or CN (n=16) (PMID: 24997149 ).

Details

Language :
English
ISSN :
00064971 and 15280020
Volume :
142
Issue :
1, Number 1 Supplement 1
Database :
Supplemental Index
Journal :
Blood
Publication Type :
Periodical
Accession number :
ejs64700775
Full Text :
https://doi.org/10.1182/blood-2023-184559