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STEROID BIOSYNTHESIS. RELATIVE EFFICIENCIES OF ENZYMIC TRANSFORMATION OF TERMINALLY MODIFIED SQUALENE 2,3-OXIDE ANALOGS INTO LANOSTEROL ANALOGS BY 2,3-OXIDOSQUALENE CYCLASE
- Source :
- Chemistry Letters; December 1973, Vol. 2 Issue: 12 p1289-1292, 4p
- Publication Year :
- 1973
-
Abstract
- The incubation of terminally modified squalene 2,3-oxide analogs with the enzyme preparation of hog liver yielded the corresponding lanosterol analogs, respectively, at different conversion rates. The interaction of 2,3-oxidosqualene cyclase with the substrates has thus been found to be influenced by the bulk of the terminal moiety.
Details
- Language :
- English
- ISSN :
- 03667022 and 13480715
- Volume :
- 2
- Issue :
- 12
- Database :
- Supplemental Index
- Journal :
- Chemistry Letters
- Publication Type :
- Periodical
- Accession number :
- ejs64652761
- Full Text :
- https://doi.org/10.1246/cl.1973.1289