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Bioavailability and daily requirement of vitamin B12in adult humans: an observational study of its colonic absorption and daily excretion as measured by [13C]-cyanocobalamin kinetics

Authors :
Kurpad, Anura V.
Pasanna, Roshni M.
Hegde, Shalini G.
Patil, Mallikarjun
Mukhopadhyay, Arpita
Sachdev, Harshpal S.
Bhat, Kishor G.
Sivadas, Ambily
Devi, Sarita
Source :
The American Journal of Clinical Nutrition; December 2023, Vol. 118 Issue: 6 p1214-1223, 10p
Publication Year :
2023

Abstract

Clinical and biochemical vitamin B12(B12) deficiency is lower than anticipated in vegetarians. Extraileal absorption, such as from the colon, as well as reduced daily excretion, may be adaptive mechanisms to maintain B12homeostasis with marginal intakes.

Details

Language :
English
ISSN :
00029165 and 19383207
Volume :
118
Issue :
6
Database :
Supplemental Index
Journal :
The American Journal of Clinical Nutrition
Publication Type :
Periodical
Accession number :
ejs64579548
Full Text :
https://doi.org/10.1016/j.ajcnut.2023.08.020