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13.2 MG INTRANASAL EPINEPHRINE TREATMENT IN CONGESTION SHOWS INCREASED BIOAVAILABILITY WITHOUT PHARMACOKINETIC AND PHARMACODYNAMIC CORRELATION

Authors :
Dworaczyk, D.
Hunt, A.
Lor, M.
Spirito, M. Di
Source :
Annals of Allergy, Asthma & Immunology; November 2023, Vol. 131 Issue: 5, Number 5 Supplement 1 pS15-S15, 1p
Publication Year :
2023

Abstract

13.2 mg intranasal (IN/NDS1C) epinephrine demonstrates rapid absorption and overall exposure that increases with allergen-induced nasal congestion. The relationship between pharmacokinetics (PK) and pharmacodynamics (PD) was explored.

Details

Language :
English
ISSN :
10811206
Volume :
131
Issue :
5, Number 5 Supplement 1
Database :
Supplemental Index
Journal :
Annals of Allergy, Asthma & Immunology
Publication Type :
Periodical
Accession number :
ejs64260533
Full Text :
https://doi.org/10.1016/j.anai.2023.08.055